{"id":10044,"date":"2026-05-12T11:19:22","date_gmt":"2026-05-12T03:19:22","guid":{"rendered":"https:\/\/hesp.tcu.edu.tw\/?p=10044"},"modified":"2026-06-05T11:21:27","modified_gmt":"2026-06-05T03:21:27","slug":"%e8%87%a8%e5%ba%8a%e8%bd%89%e8%ad%af%e6%96%b0%e5%a5%91%e6%a9%9f%ef%bc%9aps128%e7%9b%8a%e7%94%9f%e8%8f%8c%e8%88%87%e5%b8%95%e9%87%91%e6%a3%ae%e6%b0%8f%e7%97%87%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/hesp.tcu.edu.tw\/?p=10044","title":{"rendered":"\u81e8\u5e8a\u8f49\u8b6f\u65b0\u5951\u6a5f\uff1aPS128\u76ca\u751f\u83cc\u8207\u5e15\u91d1\u68ee\u6c0f\u75c7\u7814\u7a76"},"content":{"rendered":"
\"\"
\u6587\/\u5716\uff1a\u91ab\u5b78\u7cfb\u85e5\u7406\u66a8\u6bd2\u7406\u5b78\u78a9\u535a\u58eb\u73ed<\/figcaption><\/figure>\n

\u70ba\u6df1\u5316\u751f\u91ab\u7814\u7a76\u8207\u81e8\u5e8a\u61c9\u7528\u7684\u9023\u7d50\uff0c\u4e26\u62d3\u5c55\u5e2b\u751f\u5c0d\u75be\u75c5\u6a5f\u5236\u8207\u5275\u65b0\u6cbb\u7642\u7684\u7406\u89e3\uff0c\u91ab\u5b78\u7cfb\u85e5\u7406\u66a8\u6bd2\u7406\u5b78\u78a9\u535a\u58eb\u73ed\u65bc2026\u5e7405\u670812\u65e5(\u661f\u671f\u4e8c)\u7279\u9080\u76ca\u798f\u751f\u91ab\u80a1\u4efd\u6709\u9650\u516c\u53f8\u7814\u767c\u526f\u7406\u9127\u798f\u52dd\u535a\u58eb\u64d4\u4efb\u4e3b\u8b1b\u4eba\uff0c\u4ee5\u300cFrom Models to Clinical Evidence: PS128 in Parkinson\u2019s Disease\u300d\u70ba\u984c\uff0c\u6df1\u5165\u89e3\u6790\u5e15\u91d1\u68ee\u6c0f\u75c7\u7684\u81f4\u75c5\u6a5f\u5236\u8207\u76ca\u751f\u83cc\u6cbb\u7642\u7684\u65b0\u5951\u6a5f\u3002\u672c\u6b21\u8b1b\u5ea7\u9664\u85e5\u6bd2\u78a9\u535a\u58eb\u73ed\u7684\u5e2b\u751f\u5916\uff0c\u4ea6\u5438\u5f15\u4e86\u4f86\u81ea\u81e8\u5e8a\u85e5\u5b78\u7814\u7a76\u6240\u3001\u85e5\u5b78\u7cfb\u3001\u5f8c\u4e2d\u91ab\u5b78\u7cfb\u3001\u91ab\u5de5\u7cfb\u3001\u91ab\u5b78\u7cfb\u53ca\u751f\u91ab\u78a9\u58eb\u73ed\u7b49\u8de8\u7cfb\u6240\u5e2b\u751f\u517134\u4eba\u71b1\u60c5\u53c3\u8207\uff0c\u5171\u540c\u63a2\u8a0e\u8178\u9053\u83cc\u7fa4-\u8166\u8ef8(Microbiota-Gut-Brain Axis, MGBA) \u5728\u5e15\u91d1\u68ee\u6c0f\u75c7\u4e2d\u7684\u89d2\u8272\uff0c\u4ee5\u53ca\u76ca\u751f\u83ccPS128\u5728\u81e8\u5e8a\u8f49\u8b6f\u4e0a\u7684\u6f5b\u529b\u3002<\/p>\n

\u3010\u89e3\u6790PD\u81f4\u75c5\u6a5f\u5236\u8207PS128\u4e4b\u795e\u7d93\u4fdd\u8b77\u4f5c\u7528\u3011
\n\u9127\u535a\u58eb\u6307\u51fa\uff0c\u5e15\u91d1\u68ee\u6c0f\u75c7(PD)\u662f\u4e00\u7a2e\u9032\u884c\u6027\u795e\u7d93\u9000\u5316\u75be\u75c5\uff0c\u4e3b\u8981\u7279\u5fb5\u5305\u62ec\u591a\u5df4\u80fa\u795e\u7d93\u5143\u6d41\u5931\u3001\u03b1-\u7a81\u89f8\u6838\u86cb\u767d\u805a\u96c6\uff0c\u4ee5\u53ca\u591a\u6a23\u5316\u7684\u904b\u52d5\u8207\u975e\u904b\u52d5\u75c7\u72c0\u3002\u8fd1\u5e74\u4f86\uff0c\u8d8a\u4f86\u8d8a\u591a\u8b49\u64da\u986f\u793a\u8178\u8166\u8ef8\u5728PD\u7684\u767c\u75c5\u904e\u7a0b\u4e2d\u626e\u6f14\u6838\u5fc3\u89d2\u8272\uff0c\u9019\u4e5f\u70ba\u300c\u4ee5\u8178\u9053\u83cc\u7fa4\u70ba\u76ee\u6a19\u300d\u7684\u5275\u65b0\u6cbb\u7642\u63d0\u4f9b\u4e86\u79d1\u5b78\u4f9d\u64da\u3002\u9127\u535a\u58eb\u5206\u4eab\u9810\u8655\u7406(pretreatment) PS128\u5728\u4e09\u7a2e\u5177\u4ee3\u8868\u6027\u7684PD\u52d5\u7269\u6a21\u578b\u4e2d\u7684\u7814\u7a76\u6578\u64da\uff1a
\n1.MPTP\u5c0f\u9f20\u6a21\u578b\uff1a\u7814\u7a76\u8b49\u5be6PS128\u80fd\u986f\u8457\u6e1b\u7de9\u591a\u5df4\u80fa\u795e\u7d93\u5143\u7684\u9000\u5316\uff0c\u4e26\u8abf\u63a7\u7d0b\u72c0\u9ad4(Striatum)\u7684\u795e\u7d93\u50b3\u5c0e\u7269\u8cea\u6c34\u5e73\uff0c\u6709\u6548\u6291\u5236\u795e\u7d93\u767c\u708e\u53cd\u61c9\u3002
\n2.6-OHDA\u5927\u9f20\u6a21\u578b\uff1a\u89c0\u5bdf\u5230PS128\u80fd\u6539\u5584\u904b\u52d5\u529f\u80fd\u969c\u7919\uff0c\u4e26\u964d\u4f4e\u7570\u5e38\u7684\u76ae\u8ceabeta\u9707\u76ea(cortical beta oscillations)\uff0c\u986f\u793a\u5176\u5177\u5099\u8abf\u63a7\u75be\u75c5\u76f8\u95dc\u795e\u7d93\u8ff4\u8def\u529f\u80fd\u969c\u7919\u7684\u6f5b\u529b\u3002
\n3.Rotenone\u9b5a\u85e4\u7cbe\u8a98\u5c0e\u6a21\u578b\uff1a\u6b64\u6a21\u578b\u6a21\u64ec\u300c\u8178\u9053\u8d77\u6e90\u300d\u7684PD\u75c5\u7406\u7279\u5fb5\uff0c\u5be6\u9a57\u986f\u793aPS128\u4e0d\u50c5\u6539\u5584\u904b\u52d5\u8868\u73fe\uff0c\u66f4\u80fd\u8abf\u7bc0\u8178\u9053\u83cc\u7fa4\u7d44\u6210\u8207\u767c\u708e\u4fe1\u865f\u901a\u8def\uff0c\u6df1\u5165\u89e3\u6790\u76ca\u751f\u83cc\u5728\u8178\u8166\u901a\u8a0a\u4e2d\u767c\u63ee\u4f5c\u7528\u3002<\/p>\n

\u3010\u5f9e\u5be6\u9a57\u5ba4\u5230\u81e8\u5e8a\uff1a\u8f49\u8b6f\u91ab\u5b78\u7684\u5be6\u8e10\u3011
\n\u6f14\u8b1b\u4e2d\u6700\u53d7\u77da\u76ee\u7684\u90e8\u5206\u662f\u95dc\u65bc\u81e8\u5e8a\u8f49\u8b6f\u7684\u8b49\u64da\u3002\u9127\u535a\u58eb\u5206\u4eab\u4e86\u4e00\u9805\u521d\u6b65\u7684\u81e8\u5e8a\u7814\u7a76\uff0c\u7d50\u679c\u986f\u793aPD\u60a3\u8005\u5728\u7dad\u6301\u7a69\u5b9a\u7528\u85e5\u7684\u524d\u63d0\u4e0b\uff0c\u88dc\u5145PS128\u76ca\u751f\u83cc\u5341\u4e8c\u9031\u5f8c\uff0c\u904b\u52d5\u529f\u80fd\u8207\u751f\u6d3b\u54c1\u8cea\u7686\u7372\u5f97\u6539\u5584\u3002\u9019\u4e0d\u50c5\u8b49\u660e\u4e86PS128\u4f5c\u70ba\u81e8\u5e8a\u8f14\u52a9\u6cbb\u7642\u7684\u5b89\u5168\u8207\u53ef\u884c\u6027\uff0c\u4e5f\u70ba\u73fe\u5834\u5e2b\u751f\u5c55\u793a\u4e86\u5f9e\u57fa\u790e\u79d1\u7814\u8d70\u5411\u81e8\u5e8a\u61c9\u7528\u7684\u56b4\u8b39\u6b77\u7a0b\u3002<\/p>\n

\u3010\u8de8\u7cfb\u6240\u4ea4\u6d41\u8207\u570b\u969b\u8996\u91ce\u3011
\n\u5728Q&A\u4ea4\u6d41\u6642\u6bb5\uff0c\u8de8\u7cfb\u6240\u5e2b\u751f\u8a0e\u8ad6\u71b1\u70c8\u3002\u53c3\u8207\u672c\u6b21\u8b1b\u5ea7\u7684\u78a9\u58eb\u73ed\u4e00\u5e74\u7d1a\u99ac\u4f86\u897f\u4e9e\u7d1a\u5916\u7c4d\u751fMUHAMAD AZIM BIN MOHD MUNAUWAR\u8868\u793a\uff1a\u300cThe session showed how Dr. Deng combined pharmacological mechanisms with practical experience in probiotic development, offering both depth and real-world relevance.\u300d\u535a\u58eb\u73ed\u4e00\u5e74\u7d1a\u66fe\u5929\u7fa4\u540c\u5b78\u5728\u8046\u807d\u6f14\u8b1b\u5f8c\u5206\u4eab\u9053\uff1a\u300c\u9019\u5834\u6f14\u8b1b\u8b93\u6211\u66f4\u6e05\u695a\u5e15\u91d1\u68ee\u6c0f\u75c7\u7684\u6a5f\u5236\uff0c\u4e5f\u770b\u5230PS128\u5728MPTP\u30016-OHDA\u8207Rotenone\u6a21\u578b\u4e2d\u80fd\u6e1b\u5c11\u795e\u7d93\u767c\u708e\u3001\u6539\u5584\u795e\u7d93\u50b3\u5c0e\uff0c\u4e26\u5f71\u97ff\u8178\u9053\u83cc\u76f8\u3002\u6700\u4ee4\u6211\u5370\u8c61\u6df1\u523b\u7684\u662f\uff0c\u5b83\u5728\u300c\u8178\u8166\u8ef8\u300d\u67b6\u69cb\u4e0b\u5c55\u73fe\u51fa\u5f9e\u4fdd\u5065\u54c1\u8d70\u5411\u81e8\u5e8a\u8f14\u52a9\u6cbb\u7642\u7684\u6f5b\u529b\uff0c\u7814\u7a76\u65b9\u5411\u5f88\u65b0\u9bae\uff0c\u4e5f\u8b93\u6211\u601d\u8003\u5982\u4f55\u5be6\u8e10\u5f9e\u57fa\u790e\u5230\u81e8\u5e8a\u3002\u300d
\n\u672c\u6b21\u5168\u82f1\u6587\u5c08\u984c\u8b1b\u5ea7\u7d50\u5408\u56b4\u8b39\u7684\u79d1\u5b78\u6578\u64da\u8207\u6e05\u6670\u7684\u81e8\u5e8a\u8f49\u8b6f\u601d\u8def\uff0c\u70ba\u8de8\u7cfb\u6240\u5e2b\u751f\u63d0\u4f9b\u4e86\u5d84\u65b0\u7684\u7814\u7a76\u8996\u89d2\u3002\u900f\u904e\u5206\u4eab\u6700\u65b0\u7814\u7a76\u8da8\u52e2\u8207\u5be6\u52d9\u7d93\u9a57\uff0c\u6210\u529f\u5f37\u5316\u4e86\u5b78\u751f\u7684\u5c08\u696d\u7814\u7a76\u80fd\u529b\uff0c\u4e26\u547c\u61c9\u85e5\u7406\u66a8\u6bd2\u7406\u5b78\u78a9\u535a\u58eb\u73ed\u5f37\u8abf\u300c\u8207\u81e8\u5e8a\u7d50\u5408\u300d\u7684\u6559\u80b2\u76ee\u6a19\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u70ba\u6df1\u5316\u751f\u91ab\u7814\u7a76\u8207\u81e8\u5e8a\u61c9\u7528\u7684\u9023\u7d50\uff0c\u4e26\u62d3\u5c55\u5e2b\u751f\u5c0d\u75be\u75c5\u6a5f\u5236\u8207\u5275\u65b0\u6cbb\u7642\u7684\u7406\u89e3\uff0c\u91ab\u5b78\u7cfb\u85e5\u7406\u66a8\u6bd2\u7406\u5b78\u78a9\u535a\u58eb\u73ed\u65bc2026\u5e740 […]<\/p>\n","protected":false},"author":8,"featured_media":10045,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,22,27,44,47],"tags":[],"class_list":["post-10044","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sdgs-3","category-sdg-4-","category-sdg-9-","category-44","category-47"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/10044","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10044"}],"version-history":[{"count":1,"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/10044\/revisions"}],"predecessor-version":[{"id":10046,"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/posts\/10044\/revisions\/10046"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/media\/10045"}],"wp:attachment":[{"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10044"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10044"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hesp.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}