{"id":2611,"date":"2021-05-31T10:48:00","date_gmt":"2021-05-31T02:48:00","guid":{"rendered":"https:\/\/hesp.tcu.edu.tw\/?p=2611"},"modified":"2023-08-24T15:33:22","modified_gmt":"2023-08-24T07:33:22","slug":"%e8%81%b0%e6%98%8e%e7%b4%a0%e8%ad%b7%e5%a5%bd%e5%bf%83-%e6%85%88%e5%a4%a7%e6%95%99%e6%8e%88%e7%99%bc%e7%8f%be%e7%b4%a0%e9%a3%9f%e5%b0%8d%e5%bf%83%e8%a1%80%e7%ae%a1%e7%9a%84%e5%a5%bd%e8%99%95","status":"publish","type":"post","link":"https:\/\/hesp.tcu.edu.tw\/?p=2611","title":{"rendered":"\u8070\u660e\u7d20\u8b77\u597d\u5fc3 \u6148\u5927\u6559\u6388\u767c\u73fe\u7d20\u98df\u5c0d\u5fc3\u8840\u7ba1\u7684\u597d\u8655"},"content":{"rendered":"<p><a href=\"https:\/\/hesp.tcu.edu.tw\/wp-content\/uploads\/2021\/05\/1-620x414-3.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2612\" src=\"https:\/\/hesp.tcu.edu.tw\/wp-content\/uploads\/2021\/05\/1-620x414-3.jpg\" alt=\"\" width=\"620\" height=\"414\" srcset=\"https:\/\/hesp.tcu.edu.tw\/wp-content\/uploads\/2021\/05\/1-620x414-3.jpg 620w, https:\/\/hesp.tcu.edu.tw\/wp-content\/uploads\/2021\/05\/1-620x414-3-300x200.jpg 300w, https:\/\/hesp.tcu.edu.tw\/wp-content\/uploads\/2021\/05\/1-620x414-3-449x300.jpg 449w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><\/a><br \/>\n\u4f60\u5403\u7d20\u55ce\uff1f\u96a8\u8457\u6c23\u5019\u8b8a\u9077\u52a0\u5287\uff0c\u806f\u5408\u570b\u4e0d\u65b7\u5730\u547c\u7c72\u5927\u5bb6\u8981\u76e1\u53ef\u80fd\u7d20\u98df\uff0c\u56e0\u70ba\u53ea\u6709\u4eba\u4eba\u7d20\u98df\u624d\u80fd\u62ef\u6551\u4eba\u985e\u8207\u842c\u7269\u3002<!--more--><\/p>\n<p>\u4f46\u662f\uff0c\u6709\u4e9b\u4eba\u5c31\u662f\u6c92\u8fa6\u6cd5\u6297\u62d2\u8089\u98df\u7684\u8a98\u60d1\uff0c\u751a\u81f3\u6297\u62d2\u7d20\u98df\uff0c\u8a8d\u70ba\u5403\u7d20\u4e00\u5b9a\u6703\u71df\u990a\u4e0d\u826f\u2026\u904e\u53bb\u4e5f\u66fe\u6709\u7814\u7a76\u767c\u73fe\uff0c\u7d20\u98df\u8005\u56e0\u70ba\u5bb9\u6613\u9020\u6210\u7dad\u751f\u7d20B12\u7f3a\u4e4f\uff0c\u5c0e\u81f4\u534a\u540c\u80f1\u80fa\u9178\uff08L-homocysteine\uff09\u7121\u6cd5\u88ab\u8f49\u5316\u70ba\u7532\u786b\u80fa\u9178\uff08L-methionine\uff09\u3002\u534a\u540c\u80f1\u80fa\u9178\u7684\u7d2f\u7a4d\u6703\u9020\u6210\u8840\u7ba1\u5167\u76ae\u7d30\u80de\u50b7\u5bb3\u3001\u751a\u81f3\u6703\u5f15\u767c\u767c\u708e\u53cd\u61c9\uff0c\u53cd\u800c\u5bb9\u6613\u7522\u751f\u5fc3\u8840\u7ba1\u75be\u75c5\uff0c\u6240\u4ee5\u6709\u4e9b\u79d1\u5b78\u5bb6\u662f\u4e0d\u63d0\u5021\u7d20\u98df\u7684\u3002<br \/>\n\u4f46\uff0c\u7d20\u98df\u771f\u7684\u5c0d\u5fc3\u8840\u7ba1\u4e0d\u597d\u55ce\uff1f\u6148\u6fdf\u5927\u5b78\u85e5\u7406\u66a8\u6bd2\u7406\u7814\u7a76\u6240\u7684\u5289\u6649\u5b8f\u6559\u6388\uff0c\u60f3\u77e5\u9053\u73fe\u4ee3\u7d20\u98df\u8005\u662f\u5426\u4ecd\u6703\u6709\u76f8\u540c\u7684\u554f\u984c\uff1b\u65bc\u662f\u900f\u904e\u8207\u6148\u6fdf\u91ab\u9662\u5408\u4f5c\uff0c\u5206\u6790\u4e8663\u540d\u5065\u5eb7\u6210\u4eba\uff0832\u540d\u86cb\u5976\u7d20\u300131\u540d\u8477\u98df\uff09\u9ad4\u5167\u7684\u5fc3\u8840\u7ba1\u76f8\u95dc\u6307\u6a19(biomarkers)\uff0c\u767c\u73fe\u5982\u679c\u80fd\u8070\u660e\u5730\u5403\u7d20\uff0c\u4e0d\u4f46\u4e0d\u7528\u64d4\u5fc3\u7dad\u751f\u7d20B12\u7f3a\u4e4f\uff0c\u9084\u5c0d\u5fc3\u8840\u7ba1\u6709\u597d\u8655\u5462\uff01<br \/>\n\u9996\u5148\uff0c\u5289\u6649\u5b8f\u6559\u6388\u7684\u7814\u7a76\u5718\u968a\u5148\u89c0\u5bdf\u53d7\u8a66\u8005\u8840\u6db2\u4e2d\u7684\u534a\u540c\u80f1\u80fa\u9178\u6fc3\u5ea6\u3002\u53ef\u80fd\u662f\u7531\u65bc\u9019\u4e9b\u7d20\u98df\u8005\u5011\u90fd\u77e5\u9053\u7d20\u98df\u8981\u6ce8\u610f\u88dc\u5145\u7dad\u751f\u7d20B12\uff08\u53d7\u8a66\u8005\u4e2d\u6709\u4e00\u534a\u6709\u670d\u7528\u7dad\u751f\u7d20B\u7fa4\u88dc\u5145\u5291\uff0c\u540c\u6642\u4ed6\u5011\u7684\u7532\u57fa\u4e19\u4e8c\u9178[MMA]\u7684\u6fc3\u5ea6\u4e5f\u4e26\u672a\u4e0a\u5347\uff0c\u986f\u793a\u4e26\u7121\u7dad\u751f\u7d20B12\u7f3a\u4e4f\u7684\u554f\u984c\uff09\uff0c\u4ed6\u5011\u7684\u534a\u540c\u80f1\u80fa\u9178\u6fc3\u5ea6\u4e26\u6c92\u6709\u6bd4\u8477\u98df\u7d44\u8981\u9ad8\u3002\u800c\u4e14\uff0c\u7576\u8477\u98df\u8005\u7684\u8eab\u9ad4\u8cea\u91cf\u6307\u6578\uff08BMI\uff09\u4e0a\u5347\u6642\uff0c\u534a\u540c\u80f1\u80fa\u9178\u7684\u6fc3\u5ea6\u660e\u986f\u589e\u52a0\uff0c\u4f46\u9019\u500b\u73fe\u8c61\u5728\u7d20\u98df\u8005\u4e2d\u4e26\u4e0d\u6703\u767c\u751f\u3002\u800c\u4e14\u7d20\u98df\u8005\u9ad4\u5167\u8f03\u9ad8\u7684\u7dad\u751f\u7d20C\u91cf\u4e5f\u6709\u52a9\u65bc\u6d88\u9664\u9ad4\u5167\u6240\u7522\u751f\u7684\u534a\u540c\u80f1\u80fa\u9178\u3002<br \/>\n\u63a5\u8457\uff0c\u5289\u6649\u5b8f\u6559\u6388\u7814\u7a76\u5718\u968a\u51fa\u4e4e\u610f\u6599\u5730\u767c\u73fe\uff0c\u7d20\u98df\u7d44\u8840\u6db2\u4e2d\u7684\u5de6\u65cb\u8089\u9e7c\uff08L-carnitine\uff09\u6fc3\u5ea6\u6bd4\u8477\u98df\u7d44\u8981\u9ad8\u3002\u5de6\u65cb\u8089\u9e7c\u7684\u529f\u80fd\u662f\u628a\u4e2d\u3001\u9577\u93c8\u8102\u80aa\u9178\u5e36\u5165\u7c92\u7dda\u9ad4\uff0c\u5982\u6b64\u4e00\u4f86\u8102\u80aa\u9178\u5c31\u80fd\u9032\u884c\u6c27\u5316\u3001\u7522\u751f\u5927\u91cf\u7684\u80fd\u91cf\u3002\u6240\u4ee5\uff0c\u5de6\u65cb\u8089\u9e7c\u5c0d\u8102\u80aa\u9178\u7684\u5229\u7528\u6975\u70ba\u91cd\u8981\u3002\u4e00\u822c\u4eba\u4e3b\u8981\u5f9e\u98f2\u98df\u4e2d\u7684\u8089\u985e\u8207\u6d77\u9bae\u53d6\u5f97\u5de6\u65cb\u8089\u9e7c\uff0c\u4f46\u7d20\u98df\u8005\u7121\u6cd5\u5f9e\u98f2\u98df\u4e2d\u53d6\u5f97\uff0c\u90a3\u9019\u4e9b\u7d20\u98df\u8005\u7684\u5de6\u65cb\u8089\u9e7c\u662f\u600e\u9ebc\u4f86\u7684\u5462\uff1f\u6703\u4e0d\u6703\u662f\u81ea\u5df1\u6709\u6548\u5408\u6210\u7684\u5462\uff1f<br \/>\n\u5289\u6559\u6388\u7684\u7814\u7a76\u7d50\u679c\u652f\u6301\u4e86\u9019\u500b\u7d50\u8ad6\u3002\u8981\u5408\u6210\u5de6\u65cb\u8089\u9e7c\uff0c\u9700\u8981\u96e2\u80fa\u9178\uff08L-lysine\uff09\u3001\u7532\u786b\u80fa\u9178\uff08L-methionine\uff09\u8207\u7dad\u751f\u7d20C\u5171\u540c\u53c3\u8207\u3002\u5176\u4e2d\u96e2\u80fa\u9178\u662f\u505a\u9aa8\u67b6\u3001\u7532\u786b\u80fa\u9178\u63d0\u4f9b\u7532\u57fa\uff0c\u7dad\u751f\u7d20C\u5247\u4f5c\u70ba\u53cd\u61c9\u6240\u9700\u7684\u8f14\u9176\u3002\u5289\u6559\u6388\u7684\u7814\u7a76\u5718\u968a\u767c\u73fe\uff0c\u7d20\u98df\u8005\u7684\u7532\u786b\u80fa\u9178\u8207\u7dad\u751f\u7d20C\u7684\u6fc3\u5ea6\u90fd\u6bd4\u8f03\u9ad8\uff0c\u96d6\u7136\u96e2\u80fa\u9178\u7684\u6fc3\u5ea6\u597d\u50cf\u8ddf\u8477\u98df\u8005\u5dee\u4e0d\u591a\uff0c\u4f46\u9032\u4e00\u6b65\u7684\u5206\u6790\u4e5f\u767c\u73fe\uff0c\u50c5\u6709\u5728\u7d20\u98df\u8005\u9ad4\u5167\u96e2\u80fa\u9178\u3001\u7532\u786b\u80fa\u9178\u8207\u7dad\u751f\u7d20C\u7684\u6fc3\u5ea6\u8207\u5de6\u65cb\u8089\u9e7c\u7684\u6fc3\u5ea6\u5448\u986f\u8457\u5730\u6b63\u76f8\u95dc\u6027\u3002<br \/>\n\u96d6\u7136\u5de6\u65cb\u8089\u9e7c\u5c0d\u8102\u80aa\u9178\u7684\u4ee3\u8b1d\u5f88\u91cd\u8981\uff0c\u4f46\u904e\u53bb\u4e5f\u767c\u73fe\uff0c\u5de6\u65cb\u8089\u9e7c\u5728\u8178\u9053\u83cc\u53e2\u4e2d\u53ef\u88ab\u8f49\u5316\u70ba\u6c27\u5316\u4e09\u7532\u80fa\uff08TMAO\uff0cTrimethylamine N-oxide\uff09\u3002\u6c27\u5316\u4e09\u7532\u80fa\u6703\u4fc3\u9032\u5de8\u566c\u7d30\u80de\u5806\u7a4d\u5728\u8840\u7ba1\u58c1\u3001\u6291\u5236\u81bd\u56fa\u9187\u56de\u6536\u8def\u5f91\u3001\u589e\u5f37\u8840\u5c0f\u677f\u51dd\u96c6\u6d3b\u6027\uff0c\u53ef\u80fd\u9032\u800c\u5c0e\u81f4\u7ca5\u72c0\u52d5\u8108\u786c\u5316\u8207\u8840\u7ba1\u6813\u585e\u7684\u5f62\u6210\uff0c\u589e\u52a0\u7f79\u60a3\u5fc3\u81df\u75c5\u7684\u98a8\u96aa\uff0c\u9019\u6a23\u8aaa\u8d77\u4f86\uff0c\u5de6\u65cb\u8089\u9e7c\u4f3c\u4e4e\u5c0d\u6211\u5011\u53c8\u6c92\u6709\u4ec0\u9ebc\u597d\u8655\u4e86\u3002\u4f46\u5289\u6649\u5b8f\u6559\u6388\u7684\u7814\u7a76\u5718\u968a\u4e5f\u767c\u73fe\uff0c\u7d20\u98df\u8005\u7684\u5de6\u65cb\u8089\u9e7c\u6fc3\u5ea6\u96d6\u7136\u9ad8\uff0c\u4f46\u56e0\u70ba\u9019\u4e9b\u5de6\u65cb\u8089\u9e7c\u662f\u5167\u751f\u6027\u7684\uff0c\u4e26\u4e0d\u7d93\u904e\u8178\u9053\uff0c\u6240\u4ee5\u7d20\u98df\u8005\u9ad4\u5167\u7684\u6c27\u5316\u4e09\u7532\u80fa\u6fc3\u5ea6\u4e26\u672a\u4e0a\u5347\u3002\u4e0d\u50c5\u5982\u6b64\uff0c\u5289\u6559\u6388\u7684\u7814\u7a76\u5718\u968a\u9084\u767c\u73fe\uff0c\u7d20\u98df\u8005\u7684\u5de6\u65cb\u8089\u9e7c\u6fc3\u5ea6\u8d8a\u9ad8\uff0c\u4ed6\u5011\u8840\u6db2\u4e2d\u7684\u4e09\u9178\u7518\u6cb9\u8102\u6fc3\u5ea6\u8d8a\u4f4e\uff0c\u4f46\u5728\u8477\u98df\u8005\u4e2d\u4e26\u6c92\u6709\u9019\u6a23\u7684\u73fe\u8c61\u3002<br \/>\n\u770b\u4f86\u7d20\u98df\u8005\u7684\u5167\u751f\u6027\u5de6\u65cb\u8089\u9e7c\uff0c\u4f3c\u4e4e\u6709\u964d\u8840\u8102\u7684\u529f\u6548\u3002\u5289\u6649\u5b8f\u6559\u6388\u7814\u7a76\u5718\u968a\u4e5f\u767c\u73fe\uff0c\u5de6\u65cb\u8089\u9e7c\u7684\u6fc3\u5ea6\u8207\u8840\u6db2\u4e2d\u9ad8\u5bc6\u5ea6\u8102\u86cb\u767d\uff08HDL\uff0chigh density lipoprotein\uff09\u7684\u6fc3\u5ea6\u5448\u73fe\u6b63\u76f8\u95dc\uff0c\u8207\u8840\u7cd6\u6fc3\u5ea6\u5448\u73fe\u8ca0\u76f8\u95dc\u3002<br \/>\n\u7e3d\u800c\u8a00\u4e4b\uff0c\u7d20\u98df\u8005\u56e0\u70ba\u7121\u6cd5\u5f9e\u98f2\u98df\u4e2d\u53d6\u5f97\uff0c\u6240\u4ee5\u9ad4\u5167\u53cd\u800c\u81ea\u884c\u5408\u6210\u4e86\u66f4\u591a\u7684\u5de6\u65cb\u8089\u9e7c\u4f86\u4f5c\u70ba\u4ee3\u511f\u3002\u9019\u4e9b\u5167\u751f\u6027\u7684\u5de6\u65cb\u8089\u9e7c\uff0c\u4e0d\u4f46\u56e0\u70ba\u4e0d\u6703\u7d93\u904e\u8178\u9053\uff0c\u6240\u4ee5\u4e0d\u6703\u7522\u751f\u6709\u5bb3\u7684\u6c27\u5316\u4e09\u7532\u80fa\uff0c\u53cd\u800c\u9084\u6703\u5e6b\u52a9\u6211\u5011\u964d\u8840\u8102\u3001\u63d0\u5347\u9ad8\u5bc6\u5ea6\u8102\u86cb\u767d\u3001\u964d\u8840\u7cd6\uff0c\u5c0d\u6211\u5011\u7684\u5fc3\u8840\u7ba1\u6709\u76ca\u8655\u3002\u81f3\u65bc\u5c0d\u5fc3\u8840\u7ba1\u6709\u5bb3\u7684\u534a\u540c\u80f1\u80fa\u9178\uff0c\u53ea\u8981\u7d20\u98df\u8005\u6ce8\u610f\u7dad\u751f\u7d20B12\u7684\u651d\u53d6\uff0c\u5c31\u4e0d\u7528\u64d4\u5fc3\u4e86\uff0c\u6cc1\u4e14\u7d20\u98df\u8005\u4e5f\u9084\u6709\u8f03\u591a\u7684\u7dad\u751f\u7d20C\u53ef\u4f5c\u70ba\u4fdd\u8b77\u6a5f\u5236\u3002\u6240\u4ee5\u53ea\u8981\u8070\u660e\u5730\u5403\u7d20\uff0c\u4e0d\u4f46\u4e0d\u7528\u64d4\u5fc3\u6703\u71df\u990a\u4e0d\u826f\uff0c\u5c0d\u5fc3\u8840\u7ba1\u7684\u597d\u8655\u9084\u66f4\u591a\u5462\uff01<br \/>\n\u53c3\u8003\u6587\u737b\uff1a<br \/>\nTsung-Jen Lin, Sheau-Chung Tang, Pei-Yun Liao, Rachmad Anres Dongoran, Jen-Hung Yang, Chin-Hung Liu, A comparison of L-carnitine and several 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